1 17 β - hydroxyestra - 4 , 9 , 11 - trien - 3 - one ( Trenbolone ) Exhibits Tissue Selective
نویسندگان
چکیده
17β-hydroxyestra-4,9,11-trien-3-one (Trenbolone) Exhibits Tissue Selective Anabolic 1 Activity: Effects on Muscle, Bone, Adiposity, Hemoglobin, and Prostate 2 3 Joshua F. Yarrow, Christine F. Conover, Sean C. McCoy, Judyta A. Lipinska, Cesar A. 4 Santillana, John M. Hance, Darryl F. Cannady, Tisha D. VanPelt, Joshua Sanchez, Bryan P. 5 Conrad, Jennifer E. Pingel, Thomas J. Wronski, and Stephen E. Borst 6 7 VA Medical Center, Gainesville FL, United States, 32608; Departments of Applied Physiology 8 & Kinesiology, Orthopedics & Rehabilitation, and Physiological Sciences, University of 9 Florida, Gainesville, FL, United States, 32611. 10 11 Corresponding author: 12 Joshua F. Yarrow, PhD 13 VA Medical Center, Research 151 14 1601 SW Archer Rd. 15 Gainesville FL 32608-1197 16 Phone: 352-376-1611 x 6917 17 FAX: 352-374-6142 18 [email protected] 19 Sources of Support: This work was supported by Veterans Department Merit Award to SEB. 20 Running Head: Tissue selectivity of trenbolone 21
منابع مشابه
17β-Hydroxyestra-4,9,11-trien-3-one (trenbolone) exhibits tissue selective anabolic activity: effects on muscle, bone, adiposity, hemoglobin, and prostate.
Selective androgen receptor modulators (SARMs) now under development can protect against muscle and bone loss without causing prostate growth or polycythemia. 17β-Hydroxyestra-4,9,11-trien-3-one (trenbolone), a potent testosterone analog, may have SARM-like actions because, unlike testosterone, trenbolone does not undergo tissue-specific 5α-reduction to form more potent androgens. We tested the...
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